陈文利 - 教授 - 华南师范大学生物光子学研究院

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姓名：陈文利
学历：博士
职称：教授（博士生导师）
职务：-
研究方向：自噬基因功能研究
联系电话：020-85211421-8512
电子邮箱：chenwl@scnu.edu.cn
通讯地址：广州石牌华南师范大学激光生命研究所（邮编 510631）
个人主页：

陈文利，女，教授、博士生导师。研究方向：自噬在蛋白降解中的角色；自噬在细胞吞噬纳米氧化铁过程中的角色。近年在超敏反应初期自噬的功能，自噬在糖诱导的RGS1蛋白合成及降解过程中的作用，纳米氧化铁标记内皮细胞和树突细胞的生理生化特性及自噬产生的机理等研究领域做过系列研究，在Autophagy, Biology of the Cell, Cell Transplantation, PLOS ONE, Photochem. Photobiol. Sci., Experimental Biology and Medicine, Plant Cell Rep, Magnetic Resonance Imaging, Journal of Magnetic Resonance Imaging, Acta Botanica Sinica, Luminescence等期刊上发表20余篇研究论文，SCI收录20余篇。

学习经历

2013.5—2014.4美国北卡罗来纳大学教堂山分校(UNC at Chapel Hill)生物学系从事自噬在饥饿与糖诱导下在G蛋白信号转导调节因子（RGS）合成和降解的作用研究。访问学者

2011.12—2013.4美国杜克大学环境学院（Nicholas School of the Environment）从事植物抗病过程中自噬基因功能的合作研究。访问学者

2002. 5—2003.1德国国际生物物理研究所从事生物光子学的研究,在柏林自由大学生物化学与分子生物学研究所从事分子生物学方面的实验研究（作为访问学者获DAAD资助）

1999.9—2002.12华南师范大学激光生命研究所，获博士学位

1994.9—1997.6南京农业大学生命科学学院，获硕士学位

工作经历

1997.8—今华南师范大学生命科学学院/生物光子学研究院系助教，讲师，副教授，教授。从事生物化学、细胞生物学的研究及教学工作。

学术兼职

曾担任国际刊物Journal of Chromatography A，Luminescence，Human and Experimental Toxicology，Molecular Biotechnology等的审稿人。

1. Liu HB, Wang XD, Zhang YY, Dong JJ, Ma C, Chen WL*. NADPH oxidase RBOHD contributes to autophagy and hypersensitive cell death during the plant defense response in arabidopsis thaliana. Biologia Plantarum. 2015, 59(3): 570-580

2. Wang J, Ma C, Zhang M, Yang L, Chen W*. ATG5 is required to limit cell death induced by Pseudomonas syringae in Arabidopsis and may be mediated by the salicylic acid pathway. Acta Physiol Plant. 2015, 37:1731-5

3. Zhang M, Zhou J, Wang J, Zhou Q, Fang J, Zhou C, Chen W*. Superparamagnetic iron oxide labeling limits the efficacy of rabbit immature dendritic cell vaccination by decreasing their antigen uptake ability in a lysosome- dependent manner. Biotechnol Lett 2015, 37(2): 289-298

4. Yu M, Wang J, Liu W, Qin J, Zhou Q, Wang Y, Huang H, Chen W, Ma C. Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice. Toxicology. 2014, 321: 89-95.

5. Zhou J, Yang F, Zhou Q, Yang K and Chen W*. Magnetic Resonance Imaging Tracking of Ultra Small Superparamagnetic Iron Oxide Labeled Rabbit Dendritic Cells.Experimental Biology and Medicine. 2014, 239(1):13-23.

6. Dong JJ, Chen WL*. The Role of Autophagy in Chloroplast Degradation and Chlorophagy in Immune Defenses during Pst DC3000 (AvrRps4) Infection. PLOS ONE, 2013,8(8):e73091 1-16.

7. Liang MJ, Zhou Q, Yang KR, Yang XL, Fang J, Chen WL, Huang Z. Identify changes of brain regional homogeneity in bipolar disorder and unipolar depression using resting-state fMRI. PLoS One. 2013, 8(12): e79999 1-8

8. Yang F, Yu M, Zhou Q, Chen W*, Gao P, Huang Z. Effects of iron oxide nanoparticle labeling on human endothelial cells. Cell Transplantation. 2012, 21（9）: 1805-1820.

9. Wenli Chen (one of authors). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy, 2012,8(4): 445-544.

10. Quan Zhou, Kanrong Yang, Peng Gao, Wenli Chen, Dayan Yang, Minjie Liang, and Lin Zhu. An Experimental Study on MR Imaging of Atherosclerotic Plaque With SPIO Marked Endothelial Cells in a Rabbit Model. Journal of Magnetic Resonance Imaging, 2011, 34(6):1325-32.

11. Weina Zhang, Wenli Chen*. Role of salicylic acid in alleviating photochemical damage and autophagic cell death induction of cadmium stress in Arabidopsis thaliana.Photochem. Photobiol. Sci., 2011, 10(6): 947-955.

12. Lijuan Yun, Wenli Chen*. SA and ROS are involved in methyl salicylate-induced programmed cell death in Arabidopsis thaliana.Plant Cell Rep. 2011, 30(7): 1231–1239.

13. Chen Zhiqiang, Chen Wenli*, Yang Chengwei. Effects of Exogenous Salicylic Acid on Photosynthesis in Arabidopsis Leaves Based on Fluorescence Spectra and Delayed Fluorescence Technique.Spectroscopy and Spectral Analysis, 2009, 29(8): 2208-2212.

14. Liu Yang, Junjian Dong, Wenli Chen*.Autophagy and declined photosynthesis in Arabidopsis during pathogenic Pst DC3000 infection. Acta Biophysica Sinica. 2011, 27(6):517-527.

15. Gao Lin, Zhang Weina, Chen Wenli*. Cadmium toxicity and autophagy in Arabidopsis seedlings.Acta Biophysica Sinica. 2011, 27(8):676-686.

16. Mingxi Yu.，Wenli Chen*，Zhou Q，Gao P. Study on ASTC-a-1 cells labeled with superparamagnetic iron oxide and its magnetic resonance imaging.Experimental Biology and Medicine, 2010，235(9):1053-61.

17. YuHua Bi, WenLi Chen*, WeiNa Zhang, Quan Zhou, LiJuan Yuan and Da Xing, Production of reactive oxygen species, impairment of photosynthetic function and dynamic changes of mitochondria are early events in cadmium induced cell death in Arabidopsis thaliana. Biology of the Cell, 2009,101(11)：629－643.

18. Quan Zhou, Yang Dong, Li Huang, Shihua Yang, Wenli Chen. Study of cerebrovascular reserve capacity by magnetic resonance perfusion weighted imaging and photoacoustic imaging.Magnetic Resonance Imaging, 2009, 27: 155-162.

19. Wenli Chen*, Da Xing and Roeland Van Wijk．Chemiluminescence during rice seed imbibition at different temperatures. Luminescence 2006, 21（1）: 31-35.

20. Wenli Chen*, Da Xing and Weigui Chen. Rapid Detection of Aspergillus flavus Contamination in Peanut with Novel Delayed Luminescence Spectra. Photochemistry and Photobiology, 2005，81（6）：1361-1365.

21. Wenli Chen*, Roeland Van Wijk and Da Xing. Effects of isoflurane on measurements of delayed lumininescence in Acetabularia acetabulum, Luminescence 2005, 20: 16-19.

22. Wenli Chen, Da Xing, Shici Tan, et al. Imaging of ultra-weak bio-chemiluminescence and singlet oxygen generation in germination soybean in response to wounding. Luminescence, 2003, 18(1): 37-41.

23. Wenli Chen, Da Xing, Juan Wang and Yonghong He. Rapid determination of rice seed vigour by spontaneous chemiluminescence and singlet oxygen generation during early imbibition, Luminescence, 2003, 18(1): 19-24.

24. Wenli Chen, Da Xing et al. Determination of Rice Seed Vigor with Different Aging Degrees by Ultraweak Chemiluminescence during Early Imbibition. Acta Botanica Sinica, 2002, 44(11): 1376-1379.