个人简介:

庄正飞，博士、教授级实验师，全国半导体设备和材料标准化技术委员会委员(SAC/TC203)、广东省光学学会副秘书长、中国光学学会生物医学光子学专委会委员。主持国家自然科学基金、教育部博士点基金、广东省自然科学基金、清远特色载体和人才项目、广州南沙区科技计划项目、华南师范大学优秀青年基金培育项目、公司重大横向项目近20项，获批经费超过1000万元；累计发表论文50余篇，申请发明专利等20余项。

研究方向：

（1）FRET显微镜成像系统的开发与应用研究；

（2）LED光源及光机电产品开发。

发表论文：

[1].      Xiaoke Liu, Xuening Liu, Changpo Jiang, Zhihao Liu, Chaohui Zhuang, Min Hu, Zhengfei Zhuang*. A circadian lighting method for low blue light hazard, high color rendering index, and tunable circadian stimulus. Optics and Laser Technology. 2024-109794.

[2].      Xuening Liu, Changpo Jiang, Xiaoke Liu, Zhihao Liu, Min Hu, Zhengfei Zhuang*. RGBW LED mixing temperature compensation method with high output consistency. Optics and Laser Technology. 2024-110440.

[3].      Li, Yang, Guo Yanxian, Chen Haolin, Xiao Xia, Long Fangdong, ZhongHuiging, Wang Kun, Guo Zhouyi, Zhengfei Zhuang*, Liu, Zhiming*. Flexible wearable plasmonic paper-based microfluidics with expandable channel and adjustable flow rate for portable surface-enhanced Raman scattering sweat sensing. ACS Photonics. 2023-014903.

[4].      Shuo Wang, Min Hu, Beini Sun, Tian Pang, Zhengfei Zhuang*, Tongsheng Chen*. Dependence of ghost on the incident lightangle into dichroic mirror. Journal of Biophotonics. 2023, 16(11): e202300190.

[5].      Shutong Liu, Limei Su, Han Sun, Tongsheng Chen, Min Hu and Zhengfei Zhuang*. Automated apoptosis identication in fluorescence imaging of nucleus based on histogram of oriented gradients of high-frequency wavelet coefficients. Journal of Innovative Optical Health Sciences. 2023, 16(02): 2244003.

[6].      Han Sun, Chenshuang Zhang, Ye Yuan, Lu Gao, Shixian Zhai, Hongce Chen, Qilin Tang, Zhengfei Zhuang*, Tongsheng Chen*. Automated ExEm-spFRET microscope. Microscopy and Microanalysis. 2022, 28(2): 330–337

[7].    Yang Li, Yanxian Guo, Zhengfei Zhuang*. et al. Lamellar hafnium ditelluride as an ultrasensitive surface-enhanced Raman  scattering platform for label-free detection of uric acid. Photonics Reasearch. 2021, 9(6), 1039-1047.

[8].    Lu Gao, Fangrui Lin, Danlu Han, Jieming Jiang, Chengwei Yang, Zhengfei Zhuang*, Tongsheng Chen*. Quantitative Fluorescence Resonance Energy Transfer Analysis on the Direct Interaction of Activation-2b with Histone H3/Switch-3B Protein in Arabidopsis Mesophyll Protoplasts. Journal of Fluorescence. 2021, 31:981-988.

[9].      Ao Yin, Han Sun, Hongce Chen, Zhi Liu, Qiling Tang, Ye Yuan, Zhuang Tu, Zhengfei Zhuang*, Tongsheng Chen*. Measuring calibration factors by imaging a dish of cells expressing different FRET plasmids. Cytometry Part A. 2021, 99(6): 632-640.

[10].   Zhi Liu, Zewei Luo, Hongce Chen, Ao Yin, Han Sun, Zhengfei Zhuang*, Tongsheng Chen*. Optical section structured illumination-based Förster resonance energy transfer imaging. Cytometry Part A. 2021. 1-9.

[11].   Han Sun, Ao Yin, Lu Gao, Hongce Chen, Qilin Tang, Ye Yuan, Zhi Liu, Zhengfei Zhuang*, Tongsheng Chen*. Measuring system calibration factors by unmixing the excitation-emission spectra of one dish of cells. Microscopy and Microanalysis. 2021, 1498-1505.

[12].   Yu Haihong, Zhengfei Zhuang*, et al. Photo-induced synthesis of molybdenum oxide quantum dots for surface-enhanced Raman scattering and photothermal therapy. Journal of Materials Chemistry B. 2020, 8, 1040-1048.

[13].  Yanxian Guo, Zhengfei Zhuang*, et al. Facile hot spots assembly on molybdenum oxide nanosheets via in situ decoration with gold nanoparticles. Applied Surface Science. 2019, 480 1162-1270.

[14].  Deqiu Huang, Zhengfei Zhuang*, et al. Black phosphorus-Au filter paper-based three-dimensional SERS substrate for rapid detection of foodborne bacteria. Applied Surface Science. 2019, 143825.

[15].   Zhen Wang, Zhiming Liu, Chengkang Su, Biwen Yang, Xixi Fei, Yi Li, Yuqing Hou, Henan Zhao, Yanxian Guo, Zhengfei Zhuang*, Huiqing Zhong and Zhouyi Guo. Biodegradable black phosphorus-based nanomaterials in biomedicine: Theranostic Applications. Current Medicinal Chemistry. 2019, 26:1788-1805.

[16].   Zhen Wang, Zhiming Liu, Zhengfei Zhuang*, et al. Biodegradable black phosphorus-based nanomaterials in biomedicine: Theranostic Applications. Current Medicinal Chemistry. 2018, 25:1-18.

[17].   Xuejun Qiu, Hanchuan Huang, Zhitong Huang, Zhengfei Zhuang*, Zhouyi Guo, and Songhao Liu. Effect of Red Light-Emitting Diodes Irradiation on Hemoglobin for Potential Hypertension Treatment Based on Confocal Micro-Raman Spectroscopy. Scanning. 2017: 5067867.

[18].  Guangcun Yang, Zhengfei Zhuang*, Zhouyi Guo. Facile synthesis of black phosphorus-Au nanocomposites for enhanced photothermal cancer therapy and surface-enhanced Raman scattering analysis. Biomaterials Science. 2017.

[19].  Xixi Fei, Zhengfei Zhuang* et al. One-pot green synthesis of flower-liked Au NP@GQDs nanocomposites for surface-enhanced Raman scattering. Joural of Alloys and Compounds, 2017.

[20].   Yanyue Huang，Ning Li, Zhengfei Zhuang*. Study of hemoglobin response to mid-ultraviolet (UVB) radiation using micro-Raman spectroscopy. Appl. Phys. B. 2017.

[21].   Xuejun Qiu, Ke Xiong, Xiangping Ye, Zhitong Huang, Ying Chen, Chenkang Su, Zhengfei Zhuang*, Zhuoyi Guo, Songhao Liu. Study of Molecule Variations in Human Xanthelasma Skin Based on Confocal Micro-Raman Spectroscopy. Scanning. 2015, 37, 307–312.

[22].   Yanyue Huang, Zhengfei Zhuang*. Second harmonic microscopic imaging and spectroscopic characterization in prostate pathological tissue. Scanning. 36(3): 334-337 (2014).

[23].   Si-Jin Chen, Yuan Zhang, Xiang-Ping Ye, Kun Hu, Mei-Fang Zhu, Yan-Yue Huang, Mei Zhong, Zhengfei Zhuang*. Study of the molecular variation in pre-eclampsia placenta based on micro-Raman spectroscopy. (2014). DOI: 10.1007/s00404-014-3282-9.

[24].   Meifang Zhu, Xiangping Ye, Yanyue Huang, Zhouyi Guo, Zhengfei Zhuang*, Songhao Liu. Detection of methemoglobin in whole blood based on confocal micro-Raman spectroscopy and multivariate statistical techniques. Scanning. 2014, DOI: 10.1002/sca.21143.

[25].   Zhengfei Zhuang, Ning Li, Zhou-Yi Guo, Mei-Fang Zhu, Ke Xiong, Si-Jin Chen. Study of molecule variations in Renal Tumor based on confocal Micro-Raman spectroscopy. J.Biomed. Opt. 18(3): 31103 (2013).

[26].   Ping Liu, Yan-Yue Huang, Zhou-Yi Guo, Jian-Ping Wang, Zhengfei Zhuang*, Song-Hao Liu. Discrimination of dimethyl sulphoxide diffusion coefficient in the process of optical clearing by confocal micro-Raman spectroscopy. J. Biomed. Opt. 18(2): 020507 (2013).

[27].   Zhengfei Zhuang, Mei-Fang Zhu, Zhou-Yi Guo, Song-Hao Liu. Second Harmonic Generation in 3-D Uniform Arrangement of Type I Collagen on Nonlinear Optics Microscopy. Scanning. 35(1):12-16 (2013).

[28].   Zhengfei Zhuang, Mei-Fang Zhu, Zhou-Yi Guo, Ke Xiong, Ning Li, Si-Jin Chen. Study of molecule variation in various stages of human nuclear cataracts by Micro-Raman Spectroscopy. Appl. Phys. Lett. 101(17): 173701 (2012).

[29].   Ning Li, Shao-Xin Li, Zhou-Yi Guo, Zhengfei Zhuang*, Rui Li, Ke Xiong, Si-Jin Chen, Song-Hao Liu. Micro-Raman spectroscopy Study of the Effect of Mid-Ultraviolet Radiation on erythrocyte Membrane. J. Photoch. Photobio. B: Biology. 112(7): 37–42 (2012).

[30].   Zhengfei Zhuang, Ke Xiong, Zhou-Yi Guo, Si-Jin Chen, Ning Li. Micro-Raman spectroscopy Study of Human Pterygium and Conjunctival Melanocytic Nevi. Scanning. 34(6): 395-398 (2012).

[31].   Rui Li, Zhou-Yi Guo, Zhengfei Zhuang*, Ke Xiong, Si-Jin Chen, Song-Hao Liu. Quantitative analysis of crystal violet by Raman spectroscopy. Spectroscopy. 27(3): 54-57 (2012).

[32].   Wen-Zhuo Yin, Zhou-Yi Guo, Zhengfei Zhuang*, Song-Hao Liu, Ke Xiong, Si-Jin Chen. Application of surface-enhanced Raman in skin cancer by plasma. Laser Phys. 22(5): 996-1001 (2012).

[33].   Ping Liu, Jiang-Hua Li, Zhi-wei Tu, Zhou-Yi Guo, Zhengfei Zhuang*, Yun-fei Xia. Discrimination of NPC cell lines associated with malignant types using Raman spectroscopy. Laser Phys. 22(11): 1682-1688 (2012).

[34].   Zhengfei Zhuang, Han-Ping Liu, Zhou-Yi Guo, Shuang-Mu Zhuo, Bi-Ying Yu, Xiao-Yuan Deng. Second-harmonic generation as a DNA malignancy indicator of prostate glandular epithelial cells. Chin. Phys. B. 19(4): 049501 (2010).

1.  国家自然科学基金（主持），拉曼光谱结合二次谐波成像技术对肾纤维化的早期诊断与定量分级研究；

2.  教育部博士点基金（主持），基于拉曼光谱与多光子成像技术的肾纤维化诊断与分级研究；

3.  广东省教育厅研究生联合培养基地项目（主持），意识障碍多模态感觉刺激促醒系统；

4.  广东省自然科学基金（主持），基于拉曼光谱与多光子成像的肾纤维化诊断与分级研究；

5.  广州南沙区工业与科技信息化局（联合主持），家用光子亚健康调理仪产品的中试开发；

6.  广东省中医药局项目（主持），二次谐波显微成像技术用于中药复方治疗肾纤维化的药物疗效评估研究；

7.  清远市特色载体建设项目（主持），FRET分析测试中心建设；

8.  清远市人才创业项目（主持），系列FRET分析测试仪的开发；

9.  国家自然科学基金重点项目（主要参与人），基于结构光照明的动态超分辨定量FRET显微成像研究；

10.广东省重大领域研发计划（主要参与人），荧光-FRET-无标记相位三模态活细胞超分辨成像系统的研制；

11.广州市科技计划（主持），拉曼光谱结合二次谐波成像技术对结直肠肿瘤的早期诊断与分化程度分级研究；

12.华南师范大学青年教师培育计划（主持），基于显微拉曼光谱与多光子成像的肾纤维化进程检测研究；

13.公司横向合作项目（主持），紫外到蓝光波段的光生物安全监测仪器研究；

14.公司横向合作项目（主持），智能护眼台灯及其光生物安全特性研究；

15.公司横向合作项目（主持），LED摄影灯具的研制与开发；

16.公司横向合作项目（主持），系列自动化设备的研制与开发；

17.公司横向合作项目（主持），静态检测2D/3D检测仪器-动态2D/3D检测系统。

18.指导学生获批项目，广东省科技创新战略 “攀登计划”专项资金。

获奖荣誉:

1、指导学生罗泽伟等第一届粤港澳博士博士后创新创业大赛金奖；

2、指导学生黄思齐获得德国“红点奖”评选的全球50大设计新星；

3、指导学生黄思奇获中国研究生能源装备创新设计大赛国赛三等奖；

4、指导学生黄思奇获中国研究生“双碳”创新与创意大赛国赛三等奖；

5、指导学生陈挚等获“互联网+”学生创新创业大赛银奖；

6、指导学生丁敏、郭秀峰获得“中国光谷·华为杯”第十九届中国研究生数学建 模竞赛三等奖；

7、指导学生黄思奇获“中国龙腾奖”龙腾之星全球大学生绿色设计大赛铜奖；

8、指导学生肖治宇等获生光院第二届课题设计与创新创业大赛特等奖；

9、本人获得第四届“青远杯”创新创业大赛（华南师范大学师生专场）教师组一等奖（第1名）；

10、本人获得第九届“华炬杯”一等奖（第1名）。

学术兼职：

广东省光学学会                                                          副秘书长

国家半导体照明技术标准工作组TC203                         委员

中国光学学会生物医学光子学专业委员会                      委员

华南师范大学研究生培养指导委员会                             委员

广东省光学学会激光医学与美容专业委员会                   委员