个人简介：

  周俊，博士，副研究员（硕士生导师），香江学者，香港中文大学博士后（2016年“香江学者计划”）。以第一/通讯作者（含并列）在Nature Plants、Autophagy、eLife, Plant Physiology、PLOS Pathogens、Biosensors & Bioelectronics、Journal of Experimental Botany等期刊发表SCI论文20余篇。作为项目主持人承担有国家自然科学基金青年项目，广东省科技计划项目及广州市科技计划项目各1项。

研究方向：

1）植物非经典自噬与逆境胁迫响应。我们原创性地发现ATG8介导的非经典自噬参与植物逆境适应，在病原菌入侵（eLife, 2024）及在高温胁迫过程中高尔基体的修复（Nature Plants, 2023; Autophagy, 2023）发挥重要作用，相关工作打开了植物非经典自噬功能研究的大门。我们将结合细胞生物学、分子生物学、遗传学及光学技术更深入地解析植物非经典自噬分子机制及其生物学功能。

2）植物选择性自噬受体鉴定与功能分析。利用TurboID临近标记技术等，鉴定植物细胞器选择性自噬受体。TurboID临近标记技术是一个整合化学标记、质谱分析等技术的鉴定潜在蛋白互做的新型方法，利用TurboID鉴定植物自噬受体。

3）新型植物自噬光学探针的开发与设计。开发Split GFP/FRET转基因光学探针检测植物关键发育过程中自噬活性。监测自噬活性对植物生长发育及逆境胁迫的响应过程。

代表性论文：

◆ Zhang, B., Huang, S., Guo, S., Meng, Y., Tian, Y., Zhou, Y., Chen, H., Li, X., Zhou, J.*, Chen, W.*. (2024). ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability. eLife, doi:10.7554/eLife.97206.2.

◆ Zhou, J.#*, Ma, J.#, Yang, C.#, Zhu, X., Li, J., Zheng, X., Li, X., Chen, S., Feng, L., Wang, P., Ho, M. I., Ma, W., Liao, J., Li, F., Wang, C., Zhuang, X., Jiang, L., Kang, B.-H.*, Gao, C*. (2023). A non-canonical role of ATG8 in the Golgi recovery from heat stress in plants. Nature Plants, 2023, 9: 749-765.

◆ Zheng, X., Chen, S., Gao, C.*, Zhou, J.* (2023). An emerging role of non-canonical conjugation of ATG8 proteins in plant response to heat stress. Autophagy, doi:10.1080/15548627.2023.2219161.

◆ Li, H., Liao, Y., Zheng, X., Zhuang, X., Gao, C.*, Zhou, J.* (2022). Shedding light on the role of phosphorylation in plant autophagy. FEBS letters, 596(17), 2172-2185.

◆ Yu, J., Zhou, J.* (2021). Vacuolar accumulation and colocalization is not a proper criterion for cytoplasmic soluble proteins undergoing selective autophagy. Plant Signaling & Behavior, 16(10), 1932319.

◆ Ji, C.#, Zhou, J.#, Guo, R.#, Lin, Y., Kung, C. H., Hu, S., Ng, W. Y., Zhuang, X. H., Jiang, L*. (2020). AtNBR1 is a selective autophagic receptor for AtExo70E2 in Arabidopsis. Plant Physiology, 184(2), 777-791. 

◆ Lin, Y., Guo, R., Ji, C*., Zhou, J.*, Jiang, L.* (2020). New insights into AtNBR1 as a selective autophagy cargo receptor in Arabidopsis. Plant Signaling & Behavior, 1839226.    

◆ Yin, R., Liu, X., Yu, J., Ji, Y., Liu, J., Cheng, L.*, Zhou, J.* (2020). Up-regulation of autophagy by low concentration of salicylic acid delays methyl jasmonate-induced leaf senescence. Scientific Reports, 10(1), 1-10.

◆ Zhou, J., Cheng, M., Zeng, L., Liu, W., Zhang, T., & Xing, D.* (2016). Specific capture of the hydrolysate on magnetic beads for sensitive detecting plant vacuolar processing enzyme activity. Biosensors and Bioelectronics, 79, 881-886.

◆ Zhou, J., Zeng, L., Liu, J., Xing, D.* (2015). Manipulation of the xanthophyll cycle increases plant susceptibility to Sclerotinia sclerotiorum. PLOS Pathogens, 11(5): e1004878.

◆ Zhou, J., Sun, A., Xing, D.* (2013). Modulation of cellular redox status by thiamine-activated NADPH oxidase confers Arabidopsis resistance to Sclerotinia sclerotiorum. Journal of Experimental Botany. 64(11): 3261-3272.